A large retrospective study on 1PN embryo transfer supports the need for updated harmonized best practice guidelines
Listen to this summary
The authors aimed to investigate whether the genetic and clinical outcomes of monopronuclear blastocysts (MPBs) differ between standard insemination and intracytoplasmic sperm injection (ICSI) cycles, and how these differences might affect risk stratification and clinical decision-making. They found that IVF-derived MPBs had significantly lower rates of uniparental inheritance compared to ICSI-derived MPBs, with comparable clinical outcomes to 2PN blastocysts when euploid biparental embryos were transferred. These results suggest a need for updated guidelines on the management of MPBs, particularly emphasizing a risk-stratified approach based on the fertilization method used.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from Human reproduction (Oxford, England)
View all →Jun 23, 2026 · Human reproduction (Oxford, England)
Subfertility in relation to gestational weight gain and gestational diabetes: the Norwegian Mother, Father and Child Cohort Study
Jun 22, 2026 · Human reproduction (Oxford, England)
Pathogenic variants in ACTRT3 lead to male infertility characterized by fertilization defects
Jun 21, 2026 · Human reproduction (Oxford, England)
Explainability of artificial intelligence (AI) tools in assisted reproductive technologies (ARTs): promise, clinical reality, and conceptual limits
Jun 21, 2026 · Human reproduction (Oxford, England)
Ultra-rapid versus conventional oocyte vitrification: a comparative study of clinical and molecular outcomes with single-cell transcriptomic insights
Jun 18, 2026 · Human reproduction (Oxford, England)
Natural versus artificial cycle for endometrial preparation in ovulatory women undergoing frozen-thawed embryo transfer: a randomised controlled trial
Jun 18, 2026 · Human reproduction (Oxford, England)
A population-based study of the co-occurrence of hypospadias and congenital heart defects among boys conceived with in vitro fertilization†
More in Obstetrics & Gynecology
View all →Jun 25, 2026 · Prenatal diagnosis
Prenatal Genetic Testing for Beckwith-Wiedemann Syndrome: Considerations, Challenges and Observations (A Real-World Study)
Jun 25, 2026 · Prenatal diagnosis
Association of Fetal Cerebrovascular Resistance and Neurodevelopment in Congenital Heart Disease: A Physiology-Based Analysis
Jun 25, 2026 · International urogynecology journal
Predictors of Perceived Sports Performance in Female Athletes: The Role of Pelvic Floor Dysfunction and Sleep Quality
Jun 25, 2026 · Menopause (New York, N.Y.)
Processed foods in the context of a vegan diet, and changes in body weight and severe hot flashes in postmenopausal women: a secondary analysis of a randomized clinical trial
Jun 25, 2026 · BMC women's health
Mediterranean diet adherence and metabolic parameters in women with polycystic ovary syndrome: a retrospective cross-sectional study
Jun 25, 2026 · BMC women's health
Does surgeon expertise influence long-term outcomes in ovarian endometrioma rupture cases?
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
