Ultra-rapid versus conventional oocyte vitrification: a comparative study of clinical and molecular outcomes with single-cell transcriptomic insights
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This study investigates whether ultra-rapid vitrification-warming (URV/W) of oocytes, which reduces the procedure time to one minute, maintains oocyte viability and improves clinical outcomes compared to conventional vitrification-warming (CV/W) that takes 14 minutes. The findings indicate that URV/W enhances oocyte survival and is associated with fewer transcriptomic alterations, suggesting it may be a more effective method for cryopreservation. Additionally, the study provides insights into the molecular effects of both techniques on cellular stress and embryo quality.
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