June 19, 2026 · Journal of orthopaedic trauma · DOI: 10.1097/BOT.0000000000003235

Early Definitive Fixation and Risk of Deep Surgical-Site Infection After Tibial Plateau ORIF: A Systematic Review and Meta-analysis

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The authors aimed to determine whether early definitive fixation of tibial plateau fractures (TPF) reduces the risk of deep surgical-site infections (SSI) compared to delayed fixation. Their systematic review and meta-analysis of nine studies involving 1,412 patients found that early fixation within 72 hours was associated with a significantly lower risk of deep SSI and overall infection, although no significant differences were observed for other complications. The findings suggest a potential benefit of early fixation, but the authors caution that causality cannot be established from this analysis.

Justin Le, Katherine Xie, Benjamin Hershfeld, Adam D Bitterman, Michael S Linn

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