June 17, 2026 · Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · DOI: 10.1002/jum.70339

Low Intensity Pulsed Ultrasound Alleviates the Pain of Monosodium Iodoacetate-Induced Osteoarthritis in Rats

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The authors investigate whether low intensity pulsed ultrasound (LIPUS) can alleviate pain and promote joint repair in a rat model of osteoarthritis induced by monosodium iodoacetate (MIA). Their findings demonstrate that LIPUS significantly reduces pain and joint damage, as evidenced by improved behavioral outcomes and histopathological analyses, suggesting its potential as a non-invasive treatment for osteoarthritis.

Zhihua Liu, Yang Dong, Peng Xu, Xia Chen

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