Therapeutic strategies for postmenopausal atherosclerosis: a systematic review of drug interventions in animal models
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This systematic review investigates the efficacy of various therapeutic interventions for postmenopausal atherosclerosis using animal models, particularly those involving ovariectomy to simulate estrogen deficiency. The authors found that estrogen-based therapies were the most extensively studied and generally improved lipid profiles and inflammatory markers, although the effectiveness varied across different models and treatment protocols. The study emphasizes the need for standardized research designs and further translation into human trials to enhance the prevention and treatment of cardiovascular disease in postmenopausal women.
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