May 26, 2026 · The Journal of urology · DOI: 10.1097/JU.0000000000005138

Comparative Analysis of Ureteral Reimplantation and Dextranomer/Hyaluronic Acid Injection Between Two Centers with Systematic Review and Meta-Analysis

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The authors aimed to compare the effectiveness and safety of dextranomer/hyaluronic acid (Dx/HA) injection versus ureteral reimplantation in treating pediatric vesicoureteral reflux (VUR) to reduce febrile urinary tract infections (fUTIs) while minimizing perioperative morbidity. Their findings indicated that while ureteral reimplantation had a lower likelihood of reoperation and postoperative UTIs, Dx/HA offered significant advantages in terms of shorter operative time and hospital stay. These results suggest the need for individualized surgical decision-making based on the specific risks and benefits associated with each procedure.

Jin Kyu Kim, Beverly Miranda, Mandy Rickard, Adree Khondker, Martina Bruniera, Mirriam Mikhail, Renee Cimpanu, Konrad M Szymanski, Martin Kaefer, Mark P Cain, Richard C Rink, Joshua Roth, Kirstan Meldrum, Benjamin Whittam, Pankaj Dangle, Nikhil V Batra, Michael E Chua, Rodrigo Romao, Joao Pippi Salle, Joana Dos Santos, Armando J Lorenzo, Rosalia Misseri

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