Developmental Pathways From Genetic Predispositions to Psychopathology in Adolescence
Listen to this summary
The authors investigate how genetic predispositions, represented by polygenic scores (PGS) for various psychopathologies, influence the development of psychopathological symptoms from childhood to adolescence. By analyzing two longitudinal cohorts, they find that PGS for neurodevelopmental issues is significantly associated with both baseline and developmental trajectories of psychopathology symptoms, suggesting it may serve as a broad indicator of susceptibility in youth.
This is one of 33,000+ journals available on OSLR. Try it free for 14 days.
Free 14-day trial. 33,000+ journals. Cancel anytime.
More from Journal of the American Academy of Child and Adolescent Psychiatry
View all →May 21, 2026 · Journal of the American Academy of Child and Adolescent Psychiatry
An Individual Participant Data Analysis: Optimizing Pharmacological Treatment in Children and Adolescents With Major Depressive Disorder
May 21, 2026 · Journal of the American Academy of Child and Adolescent Psychiatry
Study Preregistration: Do Parenting Programs Change Interrelations Among Child Attention-Deficit/Hyperactivity Disorder, Obsessive-Compulsive Disorder, Conduct Disorder Characteristics? Individual Participant Data Network Analysis
More in Psychiatry & Neurology
View all →Sep 23, 2026 · The New England journal of medicine
Etuvetidigene Autotemcel for the Treatment of Wiskott-Aldrich Syndrome
Sep 23, 2026 · The New England journal of medicine
Clinical Uses of Common Genetic Variants Associated with Common Diseases
Sep 23, 2026 · The New England journal of medicine
Phase 1 Study of Anito-cel, a d-Domain BCMA CAR T Cell for Refractory or Recurrent Myeloma
Sep 23, 2026 · The New England journal of medicine
Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis
Sep 23, 2026 · The American journal of psychiatry
Age-Associated Cognitive Deviations in Early-Onset Psychosis Patients and Their Siblings
Sep 22, 2026 · The American journal of sports medicine
Lateral Tibial Posterior Slope Induces Anterior Tibial Translation While Lateral-Medial Slope Difference Induces Internal Rotation: A Cadaveric Biomechanical Study
"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."
Dr. Jennifer Thompson
Portland, OR
Stay current without falling behind
33,000+ journals. 3-minute audio summaries. Free for 14 days.
