June 9, 2026 · Pediatric nephrology (Berlin, Germany) · DOI: 10.1007/s00467-026-07358-8

Pooled frequency of ceftriaxone-induced urolithiasis in pediatric patients: a systematic review and meta-analysis

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The authors aimed to determine the pooled frequency of ceftriaxone-induced urolithiasis in pediatric patients through a systematic review and meta-analysis. They found that approximately 7% of children receiving ceftriaxone developed urinary tract lithiasis, with significant variability based on study design and geographic region. The study highlights the need for more robust, standardized research to accurately assess the incidence and risk factors associated with this condition.

Tahneem Yaseen, Muhammad Umair Afzal, Mustafa A Alhamaidah, Amer Hayat Khan, Musarrat Rrauf Burki, Mudassar Iqbal Arain, Akram A Ashames

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