June 12, 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · DOI: 10.1093/cid/ciag328

Clinical Impact of the BIOFIRE® FILMARRAY® Pneumonia Panel in the Veterans Affairs Healthcare System: A Difference-in-Differences Study

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The authors aimed to evaluate the clinical impact of the BIOFIRE® FILMARRAY® Pneumonia Panel on antibiotic optimization and patient outcomes in ICU patients with pneumonia within the Veterans Affairs Healthcare System. Their study found that implementation of the PN Panel was associated with improved early antimicrobial de-escalation and appropriate therapy, particularly in hospitals with robust antimicrobial stewardship programs, although overall mortality rates did not differ significantly.

Nicholas S Britt, Karim Khader, Tao He, Andrea M Prinzi, Benjamin Hommel, Tristan T Timbrook, Emily M Potter, Thomas P Lodise

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