June 3, 2026 · JPEN. Journal of parenteral and enteral nutrition · DOI: 10.1002/jpen.70110

Combined GLIM-defined malnutrition and sarcopenia and the risk of 2-year mortality in adults with heart failure: A FRAGILE-HF study post hoc analysis

Listen to this summary

This study aimed to determine whether incorporating assessments of handgrip strength and fat mass index alongside GLIM-defined malnutrition improves risk stratification for 2-year mortality in older adults with heart failure. The findings revealed that patients with GLIM-defined malnutrition who also exhibited low handgrip strength or low fat mass index had significantly higher mortality risks compared to those without malnutrition and with normal muscle and fat metrics. Thus, the study suggests that these additional assessments can help identify high-risk subgroups in this population.

Koji Matsuo, Kentaro Kamiya, Daichi Maeda, Nobuaki Hamazaki, Shota Uchida, Masashi Yamashita, Masaaki Konishi, Takatoshi Kasai, Hiroshi Saito, Yuki Ogasahara, Takeshi Kitai, Kentaro Iwata, Kentaro Jujo, Hiroshi Wada, Emi Maekawa, Shin-Ichi Momomura, Nobuyuki Kagiyama, Yuya Matsue

This is one of 33,000+ journals available on OSLR. Try it free for 14 days.

Free 14-day trial. 33,000+ journals. Cancel anytime.

14-day free trial. No commitment.

"Oslr has become part of my weekly routine on my day off. The clinical relevance of the summaries is outstanding — I'd rate it 9/10. Being able to consume research hands-free is a huge advantage for busy physicians."

Dr. Jennifer Thompson

Dr. Jennifer Thompson

Portland, OR

Stay current without falling behind

33,000+ journals. 3-minute audio summaries. Free for 14 days.

Download on the App StoreGet it on Google Play