June 10, 2026 · Fertility and sterility · DOI: 10.1016/j.fertnstert.2026.06.017

Clinical Considerations in Donor Sperm Use

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This review addresses the increasing use of donor sperm and the associated clinical considerations that clinicians must navigate, including medical, genetic, psychosocial, and regulatory factors. The authors aim to provide guidance on recipient evaluation, donor selection, and emerging challenges such as donor anonymity and the impact of direct-to-consumer genetic testing on donor-conceived individuals.

Laura C Gemmell, Iris Insogna

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