Anti-Mullerian Hormone Rebound and Estradiol Changes in the Study of Women's Health Across the Nation
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The authors aimed to characterize the prevalence of re-detectable anti-Mullerian hormone (AMH) during the menopause transition and its correlation with other ovarian hormones, particularly estradiol (E2). They found that nearly 54% of women experienced AMH rebound after reaching undetectable levels, with about half of these cases also showing a concurrent increase in E2, suggesting a potential resurgence of ovarian function. Factors such as younger age at the detectable limit of AMH, lower body mass index, and lower follicle-stimulating hormone levels were associated with this rebound, highlighting the variability of ovarian hormone levels during the perimenopausal period.
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