June 1, 2026 · BJOG : an international journal of obstetrics and gynaecology · DOI: 10.1111/1471-0528.70273

Spontaneous Preterm Birth and Subsequent Cardiovascular Mortality: Linked Registry Cohort Study

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The authors aimed to determine the risk of cardiovascular mortality (CVM) in women with a history of spontaneous preterm birth (PTB). Their population-based cohort study found that women with any type of PTB, particularly those with spontaneous PTB before 32 weeks gestation, exhibited a significantly higher risk of CVM compared to those with term births. The findings suggest that while spontaneous PTB is associated with increased CVM risk, this risk is less pronounced than that associated with PTB linked to hypertensive disorders or fetal growth restriction.

Sophie M Welters, Christianne J M De Groot, Esmé I Kamphuis, Anita C J Ravelli, Ben Willem Mol, Marjon A de Boer

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