Diffusion-weighted imaging and dynamic susceptibility contrast-enhanced perfusion-weighted imaging of the non-enhancing peritumoural region predict overall survival in glioblastoma
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The authors aimed to determine the predictive value of diffusion-weighted imaging (DWI) and dynamic susceptibility contrast-enhanced perfusion-weighted imaging (DSC-PWI) parameters in the non-enhancing peritumoural region (NEPR) for overall survival in patients with IDH-wildtype glioblastoma. They found that lower relative minimum apparent diffusion coefficient (rADCmin-p) and higher relative maximum cerebral blood volume (rCBVmax-p) in the NEPR were significantly associated with shorter survival, highlighting their potential as important imaging biomarkers for prognosis in this patient population.
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