April 28, 2026 · Clinical radiology · DOI: 10.1016/j.crad.2025.107223

Ablation-first versus biopsy-first strategy in computed tomography (CT)-guided biopsy-cryoablation for pulmonary nodules: a retrospective cohort study

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This study aimed to compare the safety and diagnostic performance of ablation-first versus biopsy-first strategies in CT-guided biopsy-cryoablation for pulmonary nodules. The findings indicated that while both approaches had similar positive biopsy rates, the ablation-first strategy resulted in significantly lower rates of procedure-related complications and intraoperative bleeding. Thus, the authors suggest that the ablation-first approach may be a safer option for patients undergoing this procedure.

L Lai, F Xu, J Tu

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