Molecular Signatures of Bladder Pain Syndrome: A Systematic Review Towards Phenotype-Informed Diagnostics
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The authors aim to synthesize molecular evidence related to bladder pain syndrome (BPS) and evaluate potential biomarkers for phenotype-informed diagnostics. Their systematic review identifies four inter-related mechanistic domains underlying BPS, highlighting the need for large, well-phenotyped studies to validate biomarkers and improve diagnostic and therapeutic strategies. The findings suggest that BPS consists of biologically distinct endotypes, emphasizing the importance of a more nuanced understanding of the condition.
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