May 5, 2026 · International urogynecology journal · DOI: 10.1007/s00192-026-06651-2

Effects of Different Cystoscopic Bladder Conditions on the Therapeutic Outcomes of Intravesical Platelet-Rich Plasma Injections in Patients with Interstitial Cystitis/Bladder Pain Syndrome

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The authors aimed to evaluate the therapeutic outcomes of repeated intravesical platelet-rich plasma (PRP) injections in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) presenting with different cystoscopic bladder conditions. The study found that 50% of patients achieved treatment success, with notable improvements in bladder pain, capacity, and glomerulation grade, particularly in those with lower inflammation and higher baseline bladder capacity. These results suggest that intravesical PRP injections can be an effective treatment option for IC/BPS, especially in patients with specific bladder characteristics.

Wan-Ru Yu, Jia-Fong Jhang, Yuan-Hong Jiang, Hann-Chorng Kuo

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