May 5, 2026 · Annals of emergency medicine · DOI: 10.1016/j.annemergmed.2026.03.014

Extracorporeal Cardiopulmonary Resuscitation for Pediatric Out-of-Hospital Cardiac Arrest

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The authors aimed to compare the outcomes of extracorporeal cardiopulmonary resuscitation (ECPR) versus continued conventional CPR in pediatric patients experiencing out-of-hospital cardiac arrest (OHCA). Their retrospective cohort study found that ECPR was associated with higher one-month survival rates and favorable neurologic outcomes compared to continued CPR, although the precision of these estimates was limited by wide confidence intervals. The findings suggest potential benefits of ECPR in this population, warranting further investigation through randomized trials.

Shunsuke Amagasa, Shintaro Iwamoto, Masashi Okubo, Shu Utsumi, Masahiro Kashiura, Hideto Yasuda, Yuki Kishihara, Satoko Uematsu

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