May 5, 2026 · Annals of emergency medicine · DOI: 10.1016/j.annemergmed.2026.03.020

Mothership and Drip-and-Ship Strategies in Mechanical Thrombectomy for Acute Ischemic Stroke

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This systematic review and meta-analysis aimed to determine the comparative effectiveness of mothership versus drip-and-ship strategies for patients with acute ischemic stroke due to large vascular occlusion treated with mechanical thrombectomy. The findings suggest that the mothership approach may enhance the likelihood of achieving a favorable functional outcome (90-day mRS 0 to 2), but no significant differences were found in broader outcomes such as recanalization rates, hemorrhagic complications, or mortality.

Lei Guo, Jun Zhang, Guo Tang, Jianhong Wang, Shu Yang, Chunling Li, Yuanyuan Liu, Yang Xiang, Fuqiang Guo

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