April 29, 2026 · The western journal of emergency medicine · DOI: 10.5811/westjem.50735

Modified SIRS Criteria for Patients ≥ 65 Years with Addition of Altered Mental Status and Reduced Heart Rate for Atrioventricular Nodal Blockers

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The authors aimed to evaluate a modified systemic inflammatory response syndrome (SIRS) criteria for diagnosing sepsis in patients aged 65 and older, incorporating altered mental status and a reduced heart rate threshold for those on atrioventricular nodal blockers. Their findings indicated that the modified criteria improved sensitivity for identifying sepsis while slightly reducing specificity, ultimately identifying an additional 1.21% of septic patients in this vulnerable population.

Lauren Gould, Eden Crowsey, Tzeferaw Sahadeo, Rita Gillespie

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