Long-term follow-up of PLACE and SPECTRA trials: outcomes after successful and unsuccessful half-dose photodynamic therapy for chronic central serous chorioretinopathy

The authors aimed to evaluate and compare the long-term functional and structural outcomes of patients with chronic central serous chorioretinopathy (cCSC) who underwent successful versus unsuccessful first half-dose photodynamic therapy (PDT). Their findings indicate that patients with successful PDT experienced significantly better visual acuity and lower rates of subretinal fluid recurrence compared to those with unsuccessful treatment, although visual acuity remained stable in both groups after the initial follow-up.