March 18, 2026 · American journal of ophthalmology · DOI: 10.1016/j.ajo.2026.03.014

Outcomes and Risk Factors for Failure After PRESERFLO™ MicroShunt Implantation in a Multicenter Japanese Cohort

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The authors aimed to evaluate the real-world outcomes of PRESERFLO™ MicroShunt (PMS) implantation and identify risk factors for surgical failure in a large multicenter Japanese cohort. They found that PMS implantation significantly reduced intraocular pressure and medication use over 12 months, with complete success rates varying by criteria. Key risk factors for failure included higher medication use and prior cataract surgery, while older age and posterior tube fixation were associated with better outcomes.

Hiroki Mieno, Kazuhiko Mori, Kiyoshi Kano, Kengo Yoshii, Kumiko Kazuo, Yoko Ikeda, Morio Ueno, Yasuaki Kuwayama, Chie Sotozono

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