March 19, 2026 · American journal of ophthalmology · DOI: 10.1016/j.ajo.2026.03.017

Swept-Source OCT Angiography Vascular Metrics as Biomarkers for Renal Function in Patients with Diabetes Mellitus

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This study investigates the potential of swept-source OCT Angiography (SS-OCTA) metrics as non-invasive biomarkers for diabetic nephropathy (DN) in patients with diabetes mellitus. The authors found that non-perfusion area (NPA) is significantly associated with the presence and severity of DN, as well as with chronic kidney disease (CKD) risk categories. The results suggest that OCTA metrics could serve as valuable tools for predicting DN and assessing its severity.

Itika Garg, Margaret Duich, Chibuike Uwakwe, Karen M Wai, Jocelyn M Rodriguez, Edward S Lu, Ying Cui, Rongrong Le, Raviv Katz, Ines Lains, Filippos Vingopoulos, Jade Y Moon, Ying Zhu, Dean Eliott, Joan W Miller, Leo A Kim, Nimesh A Patel, Deeba Husain, Demetrios G Vavvas, John B Miller

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