March 20, 2026 · Neurourology and urodynamics · DOI: 10.1002/nau.70274

Gender Disparities in Procedural Management of Hunner Lesion Interstitial Cystitis

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This study investigates sex-based differences in the clinical presentation, management, and outcomes of patients with Hunner-type interstitial cystitis (HIC). The authors found that, despite similar disease severity, females reported a higher symptom burden and longer diagnostic timelines, while male sex was a predictor of repeat fulguration procedures. The findings highlight the necessity for sex-stratified approaches in diagnosing and treating HIC.

Christina Sze, Carolina Martinez Fernandez, Maali LaFrance, Francis Jefferson, Maude Carmel, Gary Lemack, Ramy Goueli

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