Grading the evidence on the effects of exercise interventions in children and adolescents during and beyond cancer treatment: an umbrella review of systematic reviews with meta-analyses
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The authors aimed to synthesize the evidence regarding the effects of exercise interventions on children and adolescents during and after cancer treatment, while also assessing the methodological quality of the studies involved. Their umbrella review identified 19 systematic reviews with meta-analyses, revealing that exercise significantly improves cardiorespiratory fitness, cognitive function, and muscle strength, although the certainty of evidence varies across outcomes. They conclude that while exercise is beneficial for certain physical and cognitive outcomes in childhood cancer, further high-quality research is needed to enhance clinical recommendations.
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