March 23, 2026 · British journal of sports medicine · DOI: 10.1136/bjsports-2025-110782

Dose-response interplay between light and moderate-to-vigorous physical activity on all-cause mortality risk: a causal inference analysis

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The authors aimed to investigate the dose-response relationship between light-intensity physical activity (LPA) and all-cause mortality risk, particularly in the context of varying levels of moderate-to-vigorous physical activity (MVPA). Using data from the UK Biobank, they found that while LPA has a non-linear effect on reducing mortality risk, this effect diminishes as MVPA levels increase, suggesting that LPA can be a valuable complement to MVPA, especially for individuals unable to engage in higher-intensity activities. The study underscores the importance of incorporating LPA into public health recommendations to enhance overall physical activity guidelines.

Mengyun Luo, Philip James Clare, Jakob Tarp, Knut Eirik Dalene, Miguel Adriano Sanchez-Lastra, Binh Nguyen, Katherine Owen, Tracy Nau, Liangkai Chen, Ulf Ekelund, Ding Ding

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