Ultrasound-Derived Muscle Biomarkers as a Gateway toward Quantitative Pediatric Frailty in Palliative Care
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The authors aim to investigate whether ultrasound-derived muscle biomarkers can be used to define pediatric frailty in children receiving palliative care. Their exploratory study found that children with advanced life-limiting conditions exhibited significant deviations in muscle ultrasound measurements from normative ranges, suggesting the potential for these biomarkers to identify frailty patterns. The findings support the need for larger studies to establish composite ultrasound indices and formal cut-points for pediatric frailty assessment.
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