Guillain-Barré Syndrome in Pregnancy: A Systematic Review of Published Case Reports and Case Series with Obstetric and Neonatal Outcomes

The authors conducted a systematic review to evaluate the maternal disease course, obstetric management, and neonatal outcomes of Guillain-Barré syndrome (GBS) occurring during pregnancy, given the fragmented evidence in existing literature. They found that GBS is associated with significant maternal morbidity, including high rates of ICU admission and mechanical ventilation, as well as notable obstetric risks such as preterm birth and cesarean delivery. The study highlights the importance of early recognition and multidisciplinary care to mitigate these risks, despite a relatively high neonatal survival rate.