Quantitative ultrasound skin thickness measurement for assessment of lower-limb lymphedema

The authors aimed to establish skin thickness cut-off values using high-frequency ultrasound (HFUS) for assessing lower limb lymphedema. Their study found that skin thickness was significantly greater in lymphedematous limbs compared to controls, with specific cut-off values identified to aid in diagnosis. The proposed method showed promise for detecting early or subclinical lymphedema, although further validation in larger studies is needed.