A novel TNtdM staging system integrating tumor deposits into N staging and reweighting T staging for nonmetastatic colorectal cancer
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The authors aimed to develop a new staging system, TNtdM, that integrates tumor deposits into N staging and reweights T staging for nonmetastatic colorectal cancer to improve prognostic accuracy. Their analysis of data from over 161,000 patients demonstrated that the TNtdM system offers superior risk stratification and better predicts cancer-specific survival compared to the existing American Joint Committee on Cancer staging system. This new framework could enhance clinical decision-making for patients with nonmetastatic colorectal cancer.
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