Immune dysregulation in depression and psychosis: summary of current evidence and future perspectives
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The authors investigate the relationship between immune dysregulation and mental health disorders, specifically depression and schizophrenia, highlighting the ongoing debate over causality and the lack of clinically useful immune biomarkers. They suggest that new methodological approaches, such as target trial emulation and functional genomics, may pave the way for advancements in precision immunopsychiatry and tailored immunomodulatory treatments.
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