August 18, 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · DOI: 10.1016/j.nuclcard.2026.102946

Retrieval-Augmented Claude Opus 4.7 and GPT-5.5 Surpass Human Performance on the Nuclear Cardiology Board Preparation Exam (and Claude Drafts a Paper About it)

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The authors aimed to determine whether next-generation large language models (LLMs) with retrieval-augmented generation (RAG) could outperform human fellows-in-training on the American Society of Nuclear Cardiology Board Preparation Exam. Their results showed that both Claude Opus 4.7 and GPT-5.5 achieved mean accuracies of over 86%, surpassing the average human score of 78% and indicating the potential of these models as effective educational tools in nuclear cardiology.

Aditya Killekar, Aakash Shanbhag, Robert J H Miller, Damini Dey, Paul B Kavanagh, Jamieson M Bourque, Lawrence M Phillips, Panithaya Chareonthaitawee, Piotr J Slomka

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