August 29, 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · DOI: 10.1016/j.nuclcard.2026.102960

Myocardial Edema, Blood Flow, and Contractility in Takotsubo Syndrome: Comparative Evaluation with CMR and PET

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The authors aimed to investigate the relationships between myocardial edema, blood flow, and left ventricular (LV) contractility in patients with Takotsubo syndrome (TTS) using cardiac magnetic resonance (CMR) and positron emission tomography (PET). Their findings indicate that increased myocardial edema correlates with reduced stress myocardial blood flow and higher coronary vascular resistance, with these abnormalities reflecting the severity of LV contractility. The study suggests that longitudinal gradients of these parameters may offer more clinical insight than global measures alone.

Yoshito Kadoya, Mohammed Alaqaili, Aun Yeong Chong, Gary R Small, Robert A deKemp, Benjamin J W Chow, Terrence D Ruddy, Rob Beanlands, D Ian Paterson, Andrew M Crean

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