August 6, 2026 · The American journal of emergency medicine · DOI: 10.1016/j.ajem.2026.07.065

Initial atropine dose of 0.5 mg versus 1 mg in unstable bradycardia: A propensity score-matched retrospective cohort study

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The authors aimed to determine the optimal initial intravenous atropine dose for treating unstable bradycardia, comparing 0.5 mg and 1.0 mg doses. Their study found that the 1.0 mg dose resulted in higher first-dose success rates and reduced need for additional treatments compared to the 0.5 mg dose. These findings suggest that a 1.0 mg dose may be more effective in managing unstable bradycardia, warranting further investigation through prospective multicenter studies.

Kamil Kokulu, Ekrem Taha Sert, Emin Hüseyin Akar, Murat Gül

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