August 4, 2026 · The western journal of emergency medicine · DOI: 10.5811/westjem.52971

Emergency Department-initiated Naltrexone for Alcohol Use Disorder: Association with Recidivism

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The authors aimed to determine whether administering naltrexone in the emergency department (ED) would reduce recidivism rates for alcohol use disorder (AUD) within 30 days post-treatment. While the overall study population showed no change in ED visit rates after naltrexone administration, frequent ED users (those with four or more visits in the preceding 90 days) experienced a significant reduction in visits following treatment. This suggests that naltrexone may be beneficial for high-frequency ED users with AUD.

Otis Warren, Jeremiah Gress, Timmy Lin, Melanie Lippmann, Gary Bubly

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