Tirzepatide and the risk of atherosclerotic cardiovascular events: population based cohort study
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The authors aimed to estimate the reduction in major adverse cardiovascular events (MACE) associated with the addition of tirzepatide to standard care in patients with type 2 diabetes and established atherosclerotic cardiovascular disease. Their population-based cohort study found that initiating tirzepatide significantly lowered the risk of MACE compared to sitagliptin, with notable reductions in myocardial infarction and infection-related events. These findings suggest that tirzepatide may offer cardiovascular benefits beyond standard treatment, highlighting its potential role in clinical practice.
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