Real-World Comparative Effectiveness of Tirzepatide and Semaglutide for Obesity: A Multicentered Study
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The authors aimed to compare the real-world effectiveness and safety of tirzepatide and semaglutide for weight loss in patients with obesity, including those with prior obesity medication use. The study found that tirzepatide led to significantly greater weight loss than semaglutide over 12 months, with fewer gastrointestinal side effects reported. These findings suggest that tirzepatide may be a more effective option for weight management in this population, though further research in diverse groups is needed.
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