June 23, 2026 · British journal of sports medicine · DOI: 10.1136/bjsports-2025-111276

Optimising exercise prescription for cancer-related fatigue, lean mass, physical function and muscle strength in women with breast cancer: a systematic review with dose-response network meta-analysis

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The authors aimed to systematically review and analyze the dose-response relationship of different exercise modalities—aerobic, resistance, and combined exercise—on cancer-related fatigue, lean mass, physical function, and muscle strength in women with breast cancer during and after treatment. They found that combined exercise was most effective for reducing fatigue and increasing lean mass, while resistance exercise was superior for enhancing physical function and muscle strength, with significant benefits observed at relatively low exercise doses. The study highlights the potential for tailored exercise prescriptions to improve outcomes in this population.

Pedro Lopez, Maria Petropoulou, Régis Radaelli, Caroline B Silveira, Talita Molinari, Cindranne Torres Muller, Priscila Casara, Francesco Bettariga, Favil Singh, Laurien M Buffart, Anderson Rech

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