GLP-1 receptor agonists and weight-loss strategies for individuals with obesity and hip or knee osteoarthritis: a scoping review

The authors conducted a scoping review to explore current weight-loss strategies for individuals with obesity and hip or knee osteoarthritis, particularly focusing on the role of glucagon-like peptide-1 receptor agonists (GLP-1-RAs). They found that while GLP-1-RAs are associated with significant weight loss and improved symptoms in knee osteoarthritis, evidence for their effectiveness in hip osteoarthritis is limited. The review suggests that GLP-1-RAs should be used as part of a comprehensive treatment approach rather than as standalone solutions.