Association of Respiratory Syncytial Virus Vaccination During Pregnancy With Adverse Obstetric and Neonatal Outcomes
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The authors aimed to evaluate the safety of the bivalent prefusion F subunit-based respiratory syncytial virus vaccine (RSVpreF) during pregnancy, specifically assessing its association with adverse obstetric and neonatal outcomes. Their findings indicate that while there was no significant increase in risks for preterm birth, stillbirth, or small-for-gestational-age birth weight among vaccinated patients, there was a statistically significant increase in the risk of hypertensive disorders of pregnancy. Overall, the study suggests a largely favorable safety profile for the RSVpreF vaccine in pregnant individuals.
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