Incisional Infiltration of Liposomal Bupivacaine in Geriatric Hip Fracture Surgery: A Randomized Parallel-Group Trial

The authors aimed to determine whether local incisional infiltration of liposomal bupivacaine (LB) provides clinically relevant analgesic benefits in geriatric patients undergoing hip fracture surgery compared to standard multimodal analgesia without LB. Although the primary outcome of resting pain at 48 hours postoperatively did not show significant differences between groups, several secondary outcomes indicated improved pain management and sleep quality in the LB group. Ultimately, the findings do not support the routine use of LB in this surgical context, highlighting the need for further research.