Perioperative Gabapentin and Opioid Requirements: A Randomized Controlled Trial
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This study aimed to determine whether preoperative gabapentin alone is noninferior to a regimen of both preoperative and postoperative gabapentin in reducing opioid prescriptions at discharge following prolapse surgery. The results showed no significant difference in opioid prescription rates between the two groups, leading to the conclusion that the noninferiority of placebo to postoperative gabapentin could not be established, as the confidence interval exceeded the predetermined margin.
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