Cervical Preparation Prior to Dilation and Evacuation Between 13 to 16 Weeks Gestation

The authors aimed to compare the outcomes of dilation and evacuation (D&E) procedures following different single-agent cervical preparation methods (buccal misoprostol, oral mifepristone, and osmotic dilators) between 13 to 16 weeks gestation. Their retrospective cohort study found no significant differences in procedure time among the methods, and while mifepristone was linked to slightly lower estimated blood loss, the clinical significance of this finding is uncertain. Overall, all methods resulted in short procedure times and few complications, suggesting that the choice of cervical preparation can be tailored to patient preferences.