May 27, 2026 · International forum of allergy & rhinology · DOI: 10.1002/alr.70190

Site-Specific Olfactory Cleft Opacification Predicts Olfactory Function and Olfactory Training Outcome in Persistent Postinfection Olfactory Dysfunction

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This study investigates how site-specific opacification within the olfactory cleft (OC) affects olfactory function and the outcomes of olfactory training in patients with persistent postinfectious olfactory dysfunction (PIOD). The authors developed a modified CT scoring system to assess OC opacification, finding that opacification in the upper posterior OC is a significant predictor of baseline olfactory function and training response. The findings suggest that this refined assessment can enhance prognostic accuracy and guide treatment strategies for patients with PIOD.

Yankun Li, Lina Chen, Yunfan Zhang, Chia-Yi Lin, Xincen Jiang, Shilong Sun, Hailing Jiang, Xinyi Ge, Zhidi Zhang, Hongping Fu, Yinghong Zhang, Dawei Wu

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