Association Between Systemic Comorbidity Burden and Glaucoma Progression: A 5-Year Cohort Study

The authors aimed to determine whether a higher systemic comorbidity burden, as measured by the age-adjusted Charlson Comorbidity Index (age-CCI), is linked to increased odds of glaucoma progression over a five-year period. Their findings indicate that each one-point increase in age-CCI correlates with a significant rise in the likelihood of progressing from early to moderate and severe stages of glaucoma, suggesting that incorporating systemic health assessments could enhance glaucoma risk stratification and management.