June 10, 2026 · Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · DOI: 10.1097/PCC.0000000000003979

Inflammatory Markers for Nosocomial Infections in Pediatric Extracorporeal Membrane Oxygenation: Single-Center Retrospective Cohort, 2017-2022

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The authors aimed to evaluate the diagnostic performance of white blood cell (WBC) count, C-reactive protein (CRP), and procalcitonin in identifying nosocomial infections in pediatric patients undergoing extracorporeal membrane oxygenation (ECMO). Their findings indicated that none of the laboratory markers had adequate discriminative ability for detecting infections, although normal values could assist in reducing unnecessary antibiotic treatments and surveillance cultures in this patient population.

Ethan L Gillett, Esma Birisci, J Blake Frazier, Michael H Stroud, Matthew P Malone

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