Approach to the Patient: Cases of Hormonal Management in Older Transgender and Gender Diverse Adults

This article addresses the management of gender-affirming hormone therapy (GAHT) in older transgender and gender diverse (TGD) adults, particularly in the context of age-related health issues such as neurocognitive disorders, cardiovascular disease, prostate cancer, bone health, and menopause. The authors aim to provide a case-based framework for healthcare providers, highlighting the lack of specific evidence-based guidelines for this population and the need for future research to establish best practices.