June 8, 2026 · Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · DOI: 10.1007/s44470-026-00103-w

Positive airway pressure-associated epiglottis-related obstruction in adult men with obstructive sleep apnea

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The authors aimed to investigate how positive airway pressure (PAP) affects ventilation and inspiratory airflow in adults with obstructive sleep apnea (OSA) who exhibit visual evidence of epiglottis-related obstruction during drug-induced sleep endoscopy (DISE). Their findings indicate that in some individuals, the presence of epiglottis-related obstruction limits the expected increases in ventilation and airflow typically associated with higher PAP levels, highlighting a potential complication in the management of OSA.

Maxwell L Weng, Daniel Vena, Andrew Wellman, Atul Malhotra, Scott A Sands, Phillip Huyett, Eric J Kezirian

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