Circulating palmitoleic acid is associated with cerebral glucose metabolism in healthy middle-aged individuals: results from the PESA prospective cohort study
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The authors aimed to investigate the relationship between circulating palmitoleic acid (POA), a biomarker of de novo lipogenesis, and cerebral glucose metabolism in healthy middle-aged individuals. Their findings revealed that higher levels of RBC POA were associated with lower cerebral glucose uptake both cross-sectionally and longitudinally, suggesting that dietary habits influencing POA levels may play a crucial role in maintaining brain health and preventing cognitive decline.
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