June 8, 2026 · The western journal of emergency medicine · DOI: 10.5811/westjem.53045

Mechanisms and Intervention Strategies for Heat Stroke-Associated Myocardial Dysfunction: A Narrative Review

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This narrative review explores the mechanisms and intervention strategies for myocardial dysfunction associated with heatstroke, a severe condition characterized by elevated body temperature and central nervous system impairment. The authors aim to elucidate the multifactorial pathophysiology of this dysfunction, which includes direct thermal damage and systemic inflammation, and emphasize the importance of early diagnosis and management strategies such as rapid cooling and hemodynamic support. The review highlights the need for further research into targeted therapies and risk stratification for effective treatment of this potentially reversible complication.

Yan Zhuang, Xiao-Huan Zhuang, Xin-Yuan Zhang, Da-Cheng Wang, Yan Yang

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